Staff Software Engineer, Security

Tempus

Chicago, Illinois, United States · Aliso Viejo, California, United StatesFull-time$160,000–$220,000Posted Oct 12, 2026

About the role

Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Job Posting TitleJob Posting TitleStaff Software Engineer, Security

Job Description SummaryJob Description SummaryThe Staff Software Engineer for Security Engineering will drive key architectural initiatives for Tempus' Security stack:

Technical Leadership & Strategy: Set the technical vision for security engineering, leading build-versus-buy decisions, IAM evolution, and cross-functional engineering best practices to scale platform innovation.

Enabling Core Identity & Authentication: Drive customer-facing systems like Single Sign-On (SSO) and modern identity standards (OAuth, SAML, SCIM) to secure access across a decentralized microservices architecture.

Supporting Agentic AI Infrastructure: Architect and secure emerging agentic controls and distributed event-based systems to ensure patient records and intellectual property are safely utilized by generative AI technologies.

Job DescriptionJob DescriptionAre you passionate about building great software products?At Tempus, software products are owned and developed by small, autonomous teams composed of developers, designers, scientists, and product managers. Our teams set the goals, build the software, deploy the code, and contribute to a growing software platform that will make a lasting impact in the fields of cancer research and precision medicine.Tempus builds software as nimble as our teams. Our modern tech stack - dynamic languages and the latest open source and cloud services - allows our teams to iterate rapidly and lead our industry in innovation. Our decentralized, microservice architecture and emphasis on loosely coupled architecture and automation allow us to deliver advanced solutions with confidence, and at scale.Why we’re looking for you:Generative AI is changing the way businesses operate, traditional IAM controls need to evolve. As the Staff Software Engineer for security engineering you will set the technical vision to ensure Tempus’ patients records and IP are safely utilized by the latest technologies.You have experience setting the technical vision and direction for a product area, advocating for proven design principles and technology choices. You know when to implement identity standards, and where they need to be innovated on.You've got several years of experience working on software development teams, and are confident leading technical analysis & design, evaluating tradeoffs, leading build and buy decisions from a technical perspective, and establishing best practices.You have experience developing and securing distributed, event-based systems at an interesting scale of transaction and/or data volumeYou've worked in fast-paced, agile environments and helped keep projects on track, troubleshoot roadblocks, write documentation, and coordinate cross-team collaboration.You collaborate well with diverse, talented teams while mentoring and learning from team members regardless of experience level.You have experience working with cloud infrastructure providers (Amazon Web Services, Google Cloud, etc), and related tools like Docker, Terraform, or Kubernetes. You’ve have familiarity with an identity management platform like Auth0, Okta, Microsoft Entra, or Ping Identity.You are a polyglot coder - you have experience with and are comfortable using a variety of programming languages and frameworks, and picking up new ones.Bonus points for:Deep knowledge of identity standards like OAuth, SCIM, and SAML.Experience with TypeScript, JavaScript, Node.JS, or Python.Experience with OAuth 2.1 emerging agentic controls.Experience with Chronicle or other SIEMs.Experience with various Authorization models, RBAC, ReBAC, ABAC, and PBAC and their implementation tradeoffs.Responsibilities for the position:Lead technical decisions for the security engineering team and implement best in class customer identity management, authorization, and observability systems across the business.Manage and improve the existing security micro-services, custom frameworks, and tooling by identifying technical gaps, incorporating new requirements, and implementing emerging standards.Work with a variety of teams cross-functionally to implement internal standards for security across a micro-service driven architecture.Work with product team members and stakeholders to discuss project priorities, scope, and trade-offs to deliver the right solutions at the right time.Discover deficiencies in engineering tooling, designs, and processes and make the case for and driving improvements.Help level-up engineering practice across Tempus through documentation, mentorship, training, and engagement with engineers.Present new technologies and ideas to the broader organization, and the ability to communicate effectively and without bias while accepting critical feedback.Lead build/buy decisions in the security domain to improve the velocity of engineering, drive down costs, and ensure secure technical excellence.

$160,000 - $220,000

The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Responsibilities

  • Set technical direction and lead security engineering decisions, including build-versus-buy choices.
  • Develop customer identity, authentication, authorization, and observability systems.
  • Improve security microservices, frameworks, tooling, and engineering standards.
  • Coordinate with product and engineering teams to scope and deliver security solutions.
  • Mentor engineers and improve engineering practices through documentation and training.

Qualifications

  • Experience setting technical vision and leading software architecture and design.
  • Experience developing and securing distributed, event-based systems at scale.
  • Experience with cloud infrastructure and tools such as AWS, Google Cloud, Docker, Terraform, or Kubernetes.
  • Familiarity with identity platforms such as Auth0, Okta, Microsoft Entra, or Ping Identity.
  • Comfort working with multiple programming languages and frameworks.
  • Strong cross-functional collaboration, communication, and mentorship skills.
  • Bonus: Knowledge of OAuth, SCIM, SAML, OAuth 2.1, SIEMs, authorization models, TypeScript, JavaScript, Node.js, or Python.

Benefits

  • Incentive compensation may be available.
  • Restricted stock units may be available.
  • Medical and other benefits may be available.

Skills mentioned

CybersecurityIdentity and Access ManagementOAuthSAMLMicroservicesEvent-Driven ArchitectureAWSTerraformTypeScriptNode.js

About Tempus

Ambry Genetics, a Tempus company, translates scientific research into clinically actionable test results based upon a deep understanding of the human genome and the biology behind genetic disease. It is a leader in genetic testing that aims to improve health by understanding the relationship between genetics and disease. Its unparalleled track record of discoveries over 25 years, and growing database that continues to expand in collaboration with academic, corporate, and pharmaceutical partners, means Ambry Genetics is first to market with innovative products and comprehensive analysis that enable clinicians to confidently inform patient health decisions. Hiring Fraud Alert: Ambry has received reports of employment scams in recent months that seek financial commitments, or requests personal information from job candidates. Unsuspecting job seekers have reported receiving unsolicited contacts by phone, email or text from individual(s) posing to be or represent Ambry recruiter(s). If you’ve experienced either of these scenarios, please visit this page to learn more about hiring fraud: https://consumer.ftc.gov/articles/job-scams. Or visit https://www.ambrygen.com/company/careers/recruitment-fraud-alert to learn more about our policy on recruitment fraud. You can confirm the legitimacy of a job posting by viewing our current open roles at https://ambrygen.com/careers.

Biotechnology Research501-1,000 employeesAliso Viejo, CA

H-1B sponsorship history

Historical employer filing data was found for Tempus. The employer record includes 140 historical certified applications. This is employer-level history, not a guarantee that this role currently offers sponsorship.