AI Full Stack Software Engineer

McKesson

Columbus, OH, United States · Atlanta, GA, United States · Alpharetta, GA, United StatesFull-timePosted Oct 12, 2026

About the role

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our innovative team at CMM. In this role, you will be instrumental in designing, developing, and deploying end-to-end AI-powered solutions that enhance our healthcare products and services. You will work across the full stack, from front-end user interfaces to back-end AI model integration and data pipelines.

Responsibilities

Develop and deliver AI-driven enterprise quality software applications.

Build scalable applications integrating Large Language Models and other AI tools (e.g. voice recognition, document parsing, image parsing, text to speech, RAG) into new and legacy codebases

Design and optimize data pipelines and datasets for AI system development and testing.

Communicate modern AI concepts (LLMs, vector databases etc.) to non-technical audiences

Iteratively craft effective prompts to maximize LLM performance and implement prompt caching strategies

Maintain prompt libraries & benchmark performance

Fine-tune & serve GPT-family, Llama

Develop AI agents Semantic Kernel

Prototype co-pilot experiences & autonomous workflows

Fully document all work at both the code level and application level.

The ability to learn and adapt in a changing environment.

Collaborate with other staff and outside stakeholders on large projects.

Must be passionate about creating solutions and solving complex problems.

Priority will be given to candidates who reside in the Atlanta, GA, and Columbus, OH metropolitan areas.

We are unable to provide sponsorship for this role presently or in the future.

Minimum Qualifications

Minimum 2+ years of experience in Software development.

Minimum 2+ years of experience in developing AI-enhanced applications using LLMs, voice, image, or speech models.

B.S. degree in Computer Science or related engineering discipline, or equivalent experience

Critical Skills

AI System Evaluation & Optimization: Proficient in sensitivity metrics (precision, recall, F1-score, AUC-ROC) and MLOps for scalable, cost-efficient AI deployment.

RAG Development: Skilled in building RAG systems from scratch or with LangChain/LlamaIndex, using vector databases for context-aware LLM applications.

LLM Cost Optimization: Expert in managing LLM costs (token pricing, input/output rates) via prompt caching, batching, and quantization.

LLM Knowledge: Deep understanding of LLM advancements (GPT-3.5 vs GPT-4 vs o1/”thinking” models) for informed model selection and tuning.

Exceptional analytical skills to extract actionable insights from data

Experience using AI coding tools (e.g. Github Copilot, Cursor, Codeium/Windsurf)

Proficiency in Python and AI related python libraries such as openai, tensorflow, pytorch

Healthcare Domain Expertise, Translate clinical/business needs into AI solutions

Proficiency in creating Node.js web apps (e.g. Express.js)

Experience with cloud (AWS/GCP/Azure)

Effective communication skills to collaborate with technical, DevOps and product management teams.

Experience with Git, Docker, and Kubernetes

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!

Responsibilities

  • Develop and deliver enterprise-quality applications powered by AI.
  • Integrate LLMs and other AI tools into new and existing applications.
  • Design and optimize data pipelines and datasets for AI development and testing.
  • Build and optimize prompts, prompt caching strategies, and prompt libraries.
  • Fine-tune and serve GPT-family and Llama models; develop AI agents and copilots.
  • Document work and collaborate with internal teams and external stakeholders.

Qualifications

  • At least 2 years of software development experience.
  • At least 2 years of experience developing AI-enhanced applications using LLMs, voice, image, or speech models.
  • Bachelor's degree in Computer Science or a related engineering discipline, or equivalent experience.
  • Knowledge of AI evaluation metrics, MLOps, RAG, vector databases, and LLM cost optimization.
  • Proficiency in Python and AI libraries such as OpenAI, TensorFlow, or PyTorch.
  • Experience building Node.js web applications and using a cloud platform such as AWS, GCP, or Azure.
  • Experience with Git, Docker, Kubernetes, and AI coding tools.
  • Strong analytical and communication skills; healthcare domain expertise is valued.

Benefits

  • Competitive compensation package.
  • Potential annual bonus and long-term incentive opportunities.
  • Employee benefits package.

Skills mentioned

PythonNode.jsLarge Language ModelsRetrieval-Augmented GenerationPrompt EngineeringAI AgentsMLOpsModel EvaluationCloud ComputingDocker

About McKesson

At McKesson Canada, our vision is to improve care in every setting — one product, one partner, one patient at a time. We partner with hospitals, physicians, pharmacies, nurses, biopharmaceutical manufacturers and others across the spectrum of care to build healthier communities. By helping our partners be as successful as possible, we work together to improve patients’ lives. - Chez McKesson Canada, notre vision est d'améliorer les soins dans tous les contextes — un produit, un partenaire, un patient à la fois. Nous travaillons en partenariat avec des hôpitaux, des médecins, des pharmacies, des infirmières, des fabricants de produits biopharmaceutiques et d'autres dans l'ensemble du système de santé pour bâtir des communautés plus saines. En aidant nos partenaires à avoir le plus de succès possible, nous travaillons ensemble pour améliorer la vie des patients.

Hospitals and Health Care10,001+ employeesSt-Laurent, Qc

H-1B sponsorship history

Historical employer filing data was found for McKesson. The employer record includes 796 historical certified applications. This is employer-level history, not a guarantee that this role currently offers sponsorship.