Senior Full-Stack Software Engineer (Machine Learning)
About the role
Company Description Clairyon Inc. is a clinical artificial intelligence company focused on transforming acute care and patient monitoring through predictive analytics and agentic AI. Built on research from leading academic institutions, Clairyon offers the CLAIRE Continuum of Care Platform, a comprehensive ecosystem of advanced clinical decision support tools. This includes the COMPOSER predictive model, which has demonstrated significant reductions in sepsis mortality, and robust post-discharge and quality monitoring solutions validated in top medical journals. By combining longitudinal electronic health records with real-time biometric sensor data, the platform enables proactive detection of high-risk conditions, automated care quality monitoring, and improved clinical documentation. Team members collaborate in a mission-driven environment aimed at improving outcomes from the emergency department to the home.
Role Description This is a full-time, on-site role based in San Diego, CA for a Senior Full-Stack Software Engineer (Machine Learning). The person in this role will design, develop, and maintain end-to-end web applications that power Clairyon’s clinical AI platform, including both front-end user interfaces and back-end services. Daily responsibilities include implementing production-grade machine learning integrations, building APIs to ingest and process real-time clinical and sensor data, and optimizing data pipelines and model serving infrastructure for performance, reliability, and security. The engineer will collaborate closely with data scientists, clinicians, and product teams to translate research models and clinical workflows into scalable, user-centric software solutions. Additional tasks include code reviews, unit and integration testing, documentation, and contributing to architectural decisions and best practices across the engineering organization.
Qualifications
Demonstrated proficiency in Full-Stack and Software Development, with strong hands-on experience in Python and TypeScript, including experience owning features from design to deployment.
Strong Back-End Web Development skills, with experience building secure, scalable APIs and services.
Experience integrating machine learning models into production systems, including model deployment, performance monitoring, and iterative improvement.
Strong, hands-on experience building AI agents and RAG architectures using modern orchestration tools (LangChain, LangFlow, DSPy).
Solid understanding of cloud platforms (e.g., AWS), containerization (Docker, Kubernetes), and CI/CD pipelines.
Proficiency with relational and non-relational databases, data modeling, and efficient query design for high-volume clinical or sensor data.
Experience with clinical and device data, including healthcare interoperability standards such as HL7 FHIR.
Experience in healthcare, healthtech, or regulated environments (HIPAA, security and compliance standards) is highly beneficial.
Commitment to writing clean, testable code and maintaining high engineering standards in a mission-driven setting.
Front-End Development expertise, including modern JavaScript frameworks and responsive UI implementation.
Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field, or equivalent practical experience (5+).
Strong collaboration and communication skills, with the ability to work effectively in cross-functional teams and with clinical stakeholders.
Responsibilities
- Design, develop, and maintain end-to-end web applications for Clairyon’s clinical AI platform
- Implement production-grade machine learning integrations
- Build APIs to ingest and process real-time clinical and sensor data
- Optimize data pipelines and model serving infrastructure for performance, reliability, and security
- Collaborate with data scientists, clinicians, and product teams
- Conduct code reviews, unit and integration testing, and documentation
Qualifications
- Proficiency in Full-Stack and Software Development with experience in Python and TypeScript
- Strong Back-End Web Development skills with experience in building secure, scalable APIs
- Experience integrating machine learning models into production systems
- Hands-on experience building AI agents and RAG architectures
- Understanding of cloud platforms, containerization, and CI/CD pipelines
- Proficiency with relational and non-relational databases
- Experience with clinical and device data and healthcare interoperability standards
- Experience in healthcare or regulated environments is beneficial
Skills mentioned
About Clairyon
Clairyon Inc. is a pioneering clinical artificial intelligence company dedicated to transforming acute care and patient monitoring through predictive analytics and agentic AI. Born from cutting-edge research at premier academic institutions, Clairyon offers the CLAIRE Continuum of Care Platform, an overarching ecosystem of advanced clinical decision support tools. This platform includes the flagship COMPOSER predictive model, proven to significantly reduce sepsis mortality (Nature Digital Medicine 2024 and 2025), alongside comprehensive post-discharge and quality monitoring solutions (NEJM AI, 2024, JAMA Network Open 2026). By integrating longitudinal electronic health records with real-time biometric sensor data, Clairyon’s platform empowers clinicians and patients to proactively detect life-threatening conditions, automate real-time care quality monitoring and clinical documentation improvement, and ultimately improve patient outcomes from the ED door to the home. For more information, visit https://www.clairyon.com/work