Staff Software Engineer, Variant Classification
LaddersAbout the role
For our client, we are seeking a Staff Software Engineer, Variant Classification to join the team of a leader in the Healthcare space.
This role will focus on building and scaling software that supports complex interpretation and classification workflows for scientific and clinical data.
The ideal candidate will partner closely with bioinformatics, laboratory, and product stakeholders to improve data translation, evidence handling, and operational efficiency.
This is an opportunity to shape reliable platforms and tools that help drive accurate results across test content and assay development initiatives.
Location: Remote - US based candidates only, no visa sponsorship available
Compensation: $100,000 – $198,000 annually
Responsibilities
Design and build tools for accurate variant interpretation
Develop and maintain systems for translating bioinformatic data
Scale and optimize storage of sample-level information
Source and maintain annotations necessary for variant interpretation
Automate evidence placement and classification for variants
Support test content and assay development initiatives
Collaborate with cross-functional teams to implement solutions that meet business and technical needs
Qualifications
Bachelor's degree and 10+ years of software development experience
10+ years of experience with Python at an intermediate level or higher
10+ years of experience with relational databases and web development frameworks
10+ years of experience with front-end technologies such as React, Angular, Vue.js, JavaScript, or TypeScript
10+ years of experience with RESTful APIs and microservices architecture
10+ years of experience with CI/CD pipelines and DevOps practices
10+ years of experience with cloud platforms such as AWS, Azure, or GCP
Benefits
Comprehensive medical, dental, and vision insurance
Life insurance and STD/LTD coverage
401(k) with employer match
Paid Time Off (PTO) or Flexible Time Off (FTO)
Tuition reimbursement program
Employee stock purchase plan
Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.
Responsibilities
- Design and build tools for accurate variant interpretation
- Develop and maintain systems for translating bioinformatic data
- Scale and optimize storage of sample-level information
- Source and maintain annotations necessary for variant interpretation
- Automate evidence placement and classification for variants
- Support test content and assay development initiatives
- Collaborate with cross-functional teams to implement solutions that meet business and technical needs
Qualifications
- Bachelor's degree and 10+ years of software development experience
- 10+ years of experience with Python at an intermediate level or higher
- 10+ years of experience with relational databases and web development frameworks
- 10+ years of experience with front-end technologies such as React, Angular, Vue.js, JavaScript, or TypeScript
- 10+ years of experience with RESTful APIs and microservices architecture
- 10+ years of experience with CI/CD pipelines and DevOps practices
- 10+ years of experience with cloud platforms such as AWS, Azure, or GCP
Benefits
- Comprehensive medical, dental, and vision insurance
- Life insurance and STD/LTD coverage
- 401(k) with employer match
- Paid Time Off (PTO) or Flexible Time Off (FTO)
- Tuition reimbursement program
- Employee stock purchase plan
Skills mentioned
About Ladders
We lead the leaders. Ladder’s community of 10 mm leading professionals come to us to be inspired, grow in their careers, and get ahead in their professional lives. We focus on the $100K+ job market, representing 25% of all jobs and about 50% of income in the US & Canada. We build data-driven tools, marketplaces, news and entertainment products for our growing audience, and the companies, recruiters, and advertisers that want to reach them. We work best with people who enjoy using their talents, commitment and hard work to achieve great successes for millions of real life users through products that impact their careers. We are deeply technology-driven -- about half the company are engineers, technical product people or product designers -- but we never build technology for technology’s sake. We’re always trying to connect our efforts to the good it can do in people’s lives.
H-1B sponsorship history
Historical employer filing data was found for Ladders. The employer record includes 8 historical certified applications. This is employer-level history, not a guarantee that this role currently offers sponsorship.