Principal Data Scientist

Optum
Eden Prairie, Minnesota, United StatesFull-time$112,700–$193,200Posted Aug 25, 2026

About the role

Optum Tech is a global leader in health care innovation. Our teams develop cutting-edge solutions that help people live healthier lives and help make the health system work better for everyone. From advanced data analytics and AI to cybersecurity, we use innovative approaches to solve some of health care's most complex challenges. Your contributions here have the potential to change lives. Ready to build the next breakthrough? Join us to start Caring. Connecting. Growing together.

The Clinical Decision Support (CDS) Engineering team, a unit within the Optum Insight Technology organization, is responsible for building commercial products that help payers and providers with administrative- and clinician-focused CDS solutions. In this role as a Principal Data Scientist, you will lead high-impact AI initiatives characterized by scale and complexity. You will architect robust, secure AI systems, train state-of-the-art transformer and multimodal models, and bridge the gap between AI research and production software engineering. By extracting deep insights from healthcare data and maintaining the highest standards of responsible and ethical AI, you will help shape the next generation of intelligent health solutions.

You'll enjoy the flexibility to work remotely * from anywhere within the U.S. as you take on some tough challenges. For all hires in the Minneapolis or Washington, D.C. area, you will be required to work in the office a minimum of four days per week.

Primary Responsibilities

Drive end-to-end generative AI and machine learning projects that have a high degree of ambiguity, scale, and complexity

Design robust AI architectures, ensuring that systems are scalable, secure, and efficient; select appropriate technologies, frameworks, and methodologies

Build machine learning models, perform proof-of-concept experiments, optimize and deploy models to production, and partner with software engineers to productionize ML models

Perform hands-on analysis and modeling of healthcare data sets to develop insights that increase business value

Run A/B experiments, gather data, and perform statistical analysis; continuously assess AI system performance and optimize algorithms and models to improve accuracy and efficiency

Establish scalable, efficient, automated processes for large-scale data analysis, machine learning model development and validation, and MLOps

Research and implement innovative machine learning approaches, evaluate emerging trends to inform solution design, and translate cutting-edge AI advancements into production-ready capabilities that can be re-used across the enterprise

Uphold ethical AI principles by embedding fairness, transparency, and accountability throughout the model development lifecycle

Mentor and help recruit AI/ML scientists and machine learning engineers to the team

You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.

Required Qualifications

10+ years of industry or academic experience in machine learning or a related data science field

5+ years of experience building machine learning models for business applications

5+ years of experience leading technical teams or complex AI/ML projects

4+ years of equivalent technical experience in software development/data science

3+ years of experience with Python programming and deep learning frameworks (e.g., PyTorch or TensorFlow)

3+ years of experience with state-of-the-art ML architectures (e.g., Transformers/LLMs, multimodal modeling) and transformer fine-tuning

Preferred Qualifications

Experience working with complex healthcare datasets and clinical/claims analytics

Practical experience with public cloud AI technology stacks, deployment, and MLOps methodologies (AWS preferred)

Experience with big data processing tools such as Hadoop and Spark

Experience with state-of-the-art ML algorithms and architectures (e.g., Transformers/LLMs, state space models such as Mamba, GNNs), legacy architecture maintenance/migration, and tradeoffs between pretraining from scratch vs. adapting foundation models

All employees working remotely will be required to adhere to UnitedHealth Group's Telecommuter Policy.

Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The salary for this role will range from $112,700 - $193,200 annually based on full-time employment. We comply with all minimum wage laws as applicable.

Application Deadline: This will be posted for a minimum of 2 business days or until a sufficient candidate pool has been collected. Job posting may come down early due to volume of applicants.

At UnitedHealth Group, our mission is to help people live healthier lives and make the health system work better for everyone. We believe everyone-of every race, gender, sexuality, age, location and income-deserves the opportunity to live their healthiest life. Today, however, there are still far too many barriers to good health which are disproportionately experienced by people of color, historically marginalized groups and those with lower incomes. We are committed to mitigating our impact on the environment and enabling and delivering equitable care that addresses health disparities and improves health outcomes - an enterprise priority reflected in our mission.

UnitedHealth Group is an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

UnitedHealth Group is a drug - free workplace. Candidates are required to pass a drug test before beginning employment.

Responsibilities

  • Drive end-to-end generative AI and machine learning projects
  • Design robust AI architectures
  • Build machine learning models and partner with software engineers
  • Perform hands-on analysis and modeling of healthcare data sets
  • Run A/B experiments and perform statistical analysis
  • Establish scalable, efficient, automated processes for data analysis
  • Research and implement innovative machine learning approaches
  • Uphold ethical AI principles and mentor team members

Qualifications

  • 10+ years of industry or academic experience in machine learning
  • 5+ years of experience building machine learning models
  • 5+ years of experience leading technical teams
  • 4+ years of equivalent technical experience in software development
  • 3+ years of experience with Python programming and deep learning frameworks

Benefits

  • Comprehensive benefits package
  • Incentive and recognition programs
  • Equity stock purchase
  • 401k contribution

Skills mentioned

PythonMachine LearningDeep LearningPyTorchTransformersFine-TuningGenerative AIMLOpsAWSApache Spark

About Optum

We’re evolving health care so everyone can have the opportunity to live their healthiest life. It’s why we put your unique needs at the heart of everything we do, making it easy and affordable to manage health and well-being. We are delivering the right care how and when it’s needed; providing support to make smarter and healthier choices; and making prescription services easier, while helping you save money along the way. It’s everything health care should be. Together, for better health. Optum is part of UnitedHealth Group (NYSE: UNH).

Hospitals and Health Care10,001+ employeesEden Prairie , MN